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魏梦雪

发布日期:2021-02-04  点击量:

姓名: 魏梦雪

民族: 汉

学历: 博士研究生

职称: 副教授

邮箱:weimengxue@nxu.edu.cn

办公室电话:

研究方向:天然产物合成、结构修饰及生物活性,有机合成方法学领域

教育背景与工作经历

2013年8月─至今,足球世界杯买球app,从事教学科研工作

2009年9月─2013年6月,兰州大学有机化学,博士(导师:樊春安教授)

2006年9月─2009年6月,宁夏大学有机化学,硕士

2002年9月─2006年7月,济南大学材料化学,学士

科研成果

近5年在天然产物合成、结构修饰及生物活性,有机合成方法学领域开展研究工作,发表学术论文25篇,其中被Org. Chem. Front.; Eur. J. Med. Chem.; Org. Lett.等国际高水平期刊收录的SCI论文15篇,累计IF > 45。主持完成国家自然科学基金项目1项(2015.1─2018.12)、主持完成宁夏自然科学基金(重点)项目1项(2017.8─2019.8)、主持完成宁夏自然科学基金(一般)项目1项(2019.5─2021.5);主持完成2019年宁夏大学本科教育教学改革研究与实践项目1项(2019─2020);主持完成宁夏大学服务地方项目2项(2018、2021);目前主持宁夏自然科学基金(优秀青年)项目1项(2021.1─2023.12);主持宁夏本科教育教学改革研究与实践项目1项(2019.9─2022.9)。授权国家发明专利3项。主持完成科技成果转化2项,技术交易额20万元。完成省级成果登记1项。参编教材1部。

代表论文15篇:

[1] Pei-Wen Yang, Xin-Xin Liu, Xue-Qiang Li andMeng-Xue Wei*, Transition metal-free and solvent-free calcium carbide promotes the formation of β-keto sulfoxide from acyl chloride and DMSO. Org. Chem. Front.,2021, 8(12), 2914–2918. (SCI,化学/有机化学1区, Top期刊, IF = 5.281)

[2] Meng-Xue Wei, Jia-Ying Yu, Xin-Xin Liu, Xue-Qiang Li*, Jin-Hui Yang, Meng-Wei Zhang, Pei-Wen Yang, Si-Si Zhang and Yu He, Synthesis and biological evaluation of novel artemisone–piperazine–tetronamide hybrids, RSC Adv.,2021, 11(30), 18333–18341. (SCI,化学3区, IF = 3.361)

[3] Meng-Xue Wei*, Jia-Ying Yu, Xin-Xin Liu, Xue-Qiang Li, Meng-Wei Zhang, Pei-Wen Yang and Jin-Hui Yang, Synthesis of artemisinin-piperazine-furan ether hybrids and evaluation ofin vitrocytotoxic activity.Eur. J. Med. Chem.,2021, 215, 113295.(SCI,医学/药物化学1区, Top期刊, IF = 6.514)

[4] Jia-Ying Yu, Xue-Qiang Li andMeng-Xue Wei*, Synthesis and biological activities of artemisinin-piperazine-dithiocarbamate derivatives.Eur. J. Med. Chem.,2019, 169, 21-28.(SCI,医学/药物化学1区, Top期刊, IF = 6.514)

[5] Meng-Xue Wei*,1, Jiao Zhang1, Fu-Li Ma, Ming Li, Jia-Ying Yu, Wei Luo and Xue-Qiang Li**, Synthesis and biological activities of dithiocarbamates containing 2(5H)-furanone-piperazine.Eur. J. Med. Chem.,2018, 155, 165-170.(SCI,医学/药物化学1区, Top期刊, IF = 6.514)

[6] Fuli Ma, Jiao Zhang, Ming Li, Jiaying Yu, Wei Luo, Xueqiang Li* andMengxue Wei*, Synthesis of Novel Matrine Derivatives Containing Furanone Skeleton and Preliminary Evaluation of Their Anticancer Activity in Vitro. Chin. J. Org. Chem.,2018, 38 (10), 2633-2638. (SCI,化学/有机化学3区,IF = 1.652)

[7] Mengxue Wei, Jian Xu, He Zhang and Xueqiang Li*, Synthesis and Anti-tumor Effect of Artemisone Derivatives. Chin. J. Org. Chem.,2015, 35 (5), 1097-1103. (SCI,化学/有机化学3区,IF = 1.652)

[8] Mengxue Wei,Xiaohui Gao, He Zhang and Xueqiang Li*, Synthesis of New Chiral γ-Alkoxy-2(5H)-furanone-piperazine-sulfonamide Compounds and Preliminary Evaluation of in Vitro Anticancer Activity. Chin. J. Org. Chem.,2015, 35 (2), 439-445. (SCI,化学/有机化学3区,IF = 1.652)

[9] Jian XU,Mengxue WEI, Guoming LI and Xueqiang LI*, Synthesis and Anti-tumor Activities of Novel Artemisone-piperazine-sulfonamide Derivatives. Chem. J. Chinese U.,2015, 36 (5), 919-926. (SCI收录, IF = 0.650)

[10]Couxi Chen,Mengxue Weiand Xueqiang Li *, Tiancai Li, Xuezhang Zhou, Rational Synthesis and Preliminary Anti-cancer Activities of 18β-Glycyrrhetinic Acid Derivatives Containing Pyridinecarboxamide. Chin. J. Org. Chem.,2015, 35 (4), 835-842. (SCI,化学/有机化学3区,IF = 1.652)

[11]Meng-Xue Wei, Cheng-Tao Wang, Ji-Yuan Du, Hu Qu, Pei-Rong Yin, Xu Bao, Xiao-Yan Ma, Xian-He Zhao, Guo-Biao Zhang,and Chun-An Fan*,Enantioselective Synthesis of Amaryllidaceae Alkaloids (+)-Vittatine, (+)-epi-Vittatine and (+)-Buphanisine.Chem. Asian J.,2013, 8 (9), 1966-1971. (SCI,化学/化学综合3区, IF = 4.568)

[12]Meng-Xue Wei, Xiao-Hui Gao, Tian-Cai Li, Chun-An Fan* and Xue-Qiang Li*, Transalkylation of N-methyl tertiary amines with 3,4-dibromobutenolides. Chin. Chem. Lett.,2013, 24 (9), 837-839. (SCI,化学/化学综合2区, IF = 6.779)

[13]Jing Li, Guo-Liang Liu, Xian-He Zhao, Ji-Yuan Du, Hu Qu, Wen-Dao Chu, Ming Ding, Cong-Yang Jin,Meng-Xue Wei, and Chun-An Fan*, Formal Synthesis of (±)-Morphine. Chem. Asian J.,2013, 8 (6), 1105-1109. (SCI,化学/化学综合3区, IF = 4.568)

[14]Guo-Biao Zhang, Fang-Xin Wang, Ji-Yuan Du, Hu Qu, Xiao-Yan Ma,Meng-Xue Wei, Cheng-Tao Wang, Qiong Li, and Chun-An Fan*, Towards the Total Synthesis of Palhinine A: Expedient Assembly of Multifunctionalized Isotwistane Ring System with Contiguous Quaternary Stereocenters. Org. Lett.,2012, 14 (14), 3696-3699. (SCI, 1区, Top期刊, IF = 6.005)

[15]Meng-Xue Wei, Lei Feng, Xue-Qiang Li*, Xue-Zhang Zhou and Zhi-HuiShao**, Synthesis of new chiral 2,5-disubstituted 1,3,4-thiadiazoles possessing γ-butenolide moiety and preliminary evaluation of in vitro anticancer activity.Eur. J. Med. Chem.,2009, 44(8), 3340-3344.(SCI,医学/药物化学1区, Top期刊, IF = 6.514)

科研成果

1、荣获宁夏自然科学优秀学术论文一等奖1项,二等奖6项。

2、荣获European Journal of Medicinal Chemistry Certificate of Outstanding Contribution in Reviewing。

3、指导国家级大学生创新实验项目2项(荣获优秀奖1项)、自治区级大学生创新实验项目3项(荣获优秀奖1项)。

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